In a recent study of antidepressants and birth defects, Paxil was linked to twice as many birth defects as other antidepressants. Company officials are quick to point out that the study doesn’t show if Paxil actually had a role in the birth defects, but if I were pregnant, I wouldn’t take the risk. If you’re on Paxil as a headache preventive or for depression and are or plan to get pregnant, please talk to your doctor about the study.